Physicians Longevity

S-Acetyl Glutathione (300 mg, 60 capsules) by Physicians Longevity

SKU: PL497
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Supports Natural Antioxidant Activity*

  • Supports healthy cell function and healthy aging
  • Supports amino acid transport across cell membranes
  • Stomach acid-resistant capsules for stability protection

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Supplement Facts
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
S-Acetyl Glutathione (Emothion™) 300 mg *
* Daily Value not established

Emothion™ is a registered trademark of Gnosis SpAUS Patent No. 6,902,912 - European Patent No. 1391517 - JP Patent No. 4342860

  • Suggested Use: Take one capsule one to two times daily on an empty stomach, or as directed by your health care practitioner.
  • Storage: Store in a cool, dry place. KEEP OUT OF REACH OF CHILDREN.
  • Warning: Do not eat freshness packet. Keep in bottle.
  • Other Ingredients: HPMC (acid-resistant vegetarian capsule), microcrystalline cellulose, stearic acid.

Glutathione functions extensively in tissues and organs throughout the body. It plays critical role in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function.[1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients - such as glutathione - that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.*[2,5]


Other Benefits of Maintaining Healthy Glutathione Levels


Much information related to mitochondrial health has surfaced in scientific literature. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS).


S-acetyl glutathione has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing ROS.[8,9] Reduction of ROS is associated with maintaining mitochondrial integrity and function, and improved mitochondrial health is believed to support overall health and energy. Use of stomach acid-resistant capsules (DRcaps) further protect stability. Laboratory data showed that S-acetyl glutathione increased intracellular glutathione and had a positive effect on many oxidative stress biomarkers.*



1. Locigno R, Pincemail J, Henno A, et al. S-Acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH-independent mechanism. Int J Oncol. 2002 Jan;20(1):69-75. [PMID: 11743644]

2. Lomaestro BM, Malone M. Glutathione in health and disease: pharmacotherapeutic issues. Ann Pharmacother. 1995 Dec;29(12):1263-7

3. [PMID: 8672832]

4. Vogel J, Cinatl J, Dauletbaev N, et al. Effects of S-acetylglutathione in cell and animal model of herpes simplex virus type 1 infection. Med Microbiol Immunol. 2005 Jan;194(1-2):55-59. [PMID: 1462435]

5. Ballatori N, Krance SM, Notenboom S, et al. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009 Mar;390(3):191-214. [PMID: 19166318]

8. Anderson ME, Nilsson M, Sims NR. Glutathione monoethyl ester prevents mitochondrial glutathione depletion during focal cerebral ischemia. Neurochem Int. 2004 Feb;44(3):153-59. [PMID: 14568558]

9. Kretzschmar M. Regulation of hepatic glutathione metabolism and its role in hepatotoxicity. Exp Toxicol Pathol. 1996 Jul;48(5):439-46. [PMID: 8765689]